Yes, I believe there is. But of course, it all depends on what you're giving up on. Giving up on your dreams, I'd say, is a big No-Go! Always try your best to follow your dreams and make it happen for you. Giving up on life - Never! It's always worthwhile. You just don't always see all the beauty in the word, and all there is to be grateful for. Giving up on people - No! Giving up on certain relationships or friendships... sometimes necessary. For both parties. As my dear friend Jean-Marie would say - Sometimes you just have to be the stronger one and cut all ties. Sometimes you have to be the stronger one and make the hard decisions.
And sometimes, you just have to let go.
What do you think?